In white adipose tissue, blocking NNMT elevated resting calorie burn, decreased adiposity, and improved insulin sensitivity in rodent models, independent of diet or activity changes (Kraus et al., Nature Medicine )
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Conventional treatments like painkillers, corticosteroids, or topical creams often provide only temporary relief from psoriatic arthritis symptoms
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Protection against oxidative damage by iron chelators: effect of lipophilic analogues and prodrugs of N,N-bis(3,4,5- trimethoxybenzyl)ethylenediamine-N,N-diacetic acid (OR10141)