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Interestingly, a study conducted by Meng et al 14 showed that TMAO could further activate CSNS and initiate arrhythmia via direct way through the left stellate ganglion and indirect mechanisms by the central nervous system

Compound 41 also inhibited the expression of COX-2 and iNOS via the NF-B pathway

Acta Orthop Scand 71:316321 Ethics declarations Conflict of interest The authors declare that they have no conflict of interest

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