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Researchers fixated on total daily exposure often make the mistake of consolidating doses into fewer, larger injections to 'simplify' the protocol
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Because foveal acuity reflects the function of less than 1 % of the retinal surface and remains remarkably preserved until relatively late in the disease, these traditional metrics are inherently blind to the diffuse neurosensory disturbance that characterizes the earliest stages of diabetic retinal disease
Five to seven days later, participants will come to our research unit, and we will conduct the standard of care OGTT alongside a supervised GTT@home, with the results of the two tests compared to assess accuracy
The neurobehavioral assessment, the volume of cerebral infarction and the morphology of neurons were measured to complete the preliminary pharmacodynamic study
