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In further research, it was found that the neuroprotection mediated by berberine after ischemia involves the AKT/glycogen synthase kinase-3 (GSK3)/extracellular signal-regulated kinase 1/2 (ERK 1/2) signal pathway, and inhibits Jun amino-terminal kinases (JNK) and caspase-3 activity (Simes Pires et al., 2014)

Link Crippa, J

MDCalc

Carter BZ, Mak DH, Morris S, Borthakur G, Estey E, Byrd AL, Konopleva M, Kantarjian HM, Andreeff M

A minimum quantity of 20,000 cells per sample was collected, and the DNA histograms were further analyzed using the ModFit LT software (Verity Software House, Topsham, ME, USA) for cell cycle analysis