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The MHRA has granted this authorisation based on new data from a clinical study which found that semaglutide reduces the incidence of major adverse cardiovascular events (MACE) by 20% when compared with a placebo

Proteins such as mitofusins 1 and 2 (Mfn1 and Mfn2), optic atrophy gene 1 (OPA1), dynamin-related protein 1 (Drp1), and fission protein 1 (Fis1) are key regulators of these processes [142]

Multiple generics are available for liraglutide (Victoza) for the treatment of T2DM

doi: 10.1038/S41586-021-03552-W 55 VahediGKannoYFurumotoYJiangKParkerSCJErdosMRet al