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Results were consistent between the intention-to-treat and on-treatment analyses, except for 6MWD where doseresponse relationship was observed in the intention-to-treat, but not in the on-treatment, analysis (Extended Data Fig

Mol Ther Nucleic Acids 20:882894

Why Weight Loss Plateaus on Semaglutide Weight loss with Ozempic or Wegovy often plateaus after 912 months as the body adapts and reaches a new balance

Retatrutide also demonstrated clinically meaningful improvements in cardiometabolic markers, including systolic blood pressure, nonhigh-density lipoprotein cholesterol, and triglycerides