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Gaining Weight on Retatrutide: Causes, Solutions, and When to Seek Help Gaining weight on retatrutide can be alarming, especially given the drug's reputation for significant weight loss in clinical trials

FDA Approval Timeline As of mid-2025, Retatrutide is: Still under investigation in phase 3 clinical trials Expected to complete primary trials by late 2025 Anticipated to receive FDA approval in 2026 Until then, it is available only for research purposes , and should not be used outside of controlled clinical settings without professional supervision

GCGR agonism has been linked to transient increases in heart rate, a variable that must be closely monitored in any experimental model involving Retatrutide

However, like any medication, they may cause side effects in some individuals

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