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Similarly, SYNCHRONIZE-CVOT (survodutide), a glucagon/GLP-1 receptor co-agonist, is being evaluated in a large-scale randomized controlled trial to assess its cardiovascular safety and efficacy in people with obesity (93)
Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism (Mari et al., 2013)
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