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If 0.1 mL contains 1 mg, then 1 mL (which is 10x larger) will contain 10 mg

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Megaloblastic anemia Diminished activity of methionine synthase in vitamin B 12 deficiency inhibits the regeneration of tetrahydrofolate (THF) and traps folate in a form that is not usable by the body ( Figure 3 ), resulting in symptoms of folate deficiency even in the presence of adequate folate

This breadth may reflect the fundamental nature of the pathways being studied, such as endothelial function, cell migration machinery, and stress-response biology, rather than a single tissue-specific receptor mechanism