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Research remains exploratory, focusing on cellular communication, pathway duration, and system-wide signaling responses rather than clinical or physiological outcomes

BACH1 is involved in various physiological processes and pathogenesis related to inflammation, oxidative stress damage, autoimmunity disorders, and cancer angiogenesis, among others [219]

10.1096/fj.201801417R FASEB J

J Asian Pac J Cancer Prev

Abbreviations ALK: Anaplastic lymphoma kinase ALL: Acute lymphoblastic leukemia EGF: Epidermal growth factor ER: Estrogen receptor FAK: Focal adhesion kinase FGF: Fibroblast growth factor HGF: Hepatocyte growth factor HNSCC: Head and neck squamous carcinoma IGF: Insulin-like growth factor IGFBP: IGF-binding protein IGF-IR: Type I insulin-like growth factor receptor IGF-IIR: Type II IGF receptor InsR: Insulin receptor mAbs: Monoclonal antibodies MAPK: Mitogen-activated protein kinase PDGF: Platelet-derived growth factor PI3K: Phosphatidylinositol 3-kinase RTK: Receptor tyrosine kinase TGF: Transforming growth factor VEGF: Vascular endothelial growth factor References Bach LA