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Across these trials, tirzepatide delivered dose-dependent improvements in glycemic control and body weight, often surpassing comparators like semaglutide and dulaglutide (43)(44)

10.1038/nrn1537 186 ZhangJ.ZhangM.YangZ.HuangS.WuX.CaoL.et al (2020a)

Difference Between the Legs : Lipedema may show a marked difference between the upper legs and the lower legs

While extensive data reassure their use, more trials are needed, particularly for populations like children, older adults, and those with severe illness

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