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Scientific reports 12(1), 2022

A potent blocker of CPT1, rate limiting for fatty acid metabolism and hence lipid metabolism, called Etomoxir is able to reverse the shift in metabolism, thereby favouring glucose metabolism as an energy source rather than lipids 16,17,18

The authors hypothesized that the physiological significance of DHAR activity depends on the ascorbate pool size and that DHARs are required only at high levels of ascorbate

Each cuvette was inverted three times to ensure complete mixing and was allowed 10 minutes for reaction to proceed to completion