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Suppose the redox balance in the body has lost its ability to repair damaged cells and regulate the immune response
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This unexpected process is known as aerobic glycolysis or Warburg effect
Its binding to VMAT2 is very strong, making it's effect appear irreversible, with trace amounts of the drug remaining bound to vesicular membranes for many days, and its clinical effects lasting many days to weeks, and may persist until new transporter proteins are synthesized (German et al, 2015
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