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Patients should be vigilant for symptoms of pancreatitis , changes in heart rate , severe gastrointestinal distress , hypoglycemia , or diabetic retinopathy when using this medication and should report any such occurrences to a healthcare provider immediately

doi: 10.3389/fcimb.2021.657775 Received 24 January 2021 Accepted 11 May 2021 Published 03 June 2021 Volume 11 - 2021 Edited by Diego Luis Costa, University of So Paulo, Brazil Reviewed by Maria Regina DImprio Lima, University of So Paulo, Brazil

Guess what they found

Combined with the appetite suppression from the GLP-1 pathway, this dual mechanism produces faster and more substantial weight loss for many patients

Increased insulin sensitivity comes next, because a leaner liver interrupts insulin less