Disease severity is likely dependent on the efficiency of alternative pathways, but not on the level of residual enzyme activity (25)
Antioxidants (Basel) 9 , 909 (2020)
1 H MRS in the muscle allows detection of multiple metabolites, of which creatine, acetyl-carnitine, carnosine and intramyocellular lipids (IMCL) have been shown to be useful biomarkers of muscle metabolism [23]
Osteoporosis research requires skeletally mature animals to avoid the many complicating factors that arise in young animals with developing bone tissue
High levels of QA also increase the production of pro-inflammatory cytokines and chemokines, such as IL-8, monocyte chemoattractant protein-1 and RANTES, as well as chemokine receptor expression, in human fetal astrocytes [119]