[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Mikus D, Sikiric P, Seiwerth S, Petricevic A, Aralica G, Druzijancic N, et al
Tumor Necrosis Factor-alpha affects melanocyte survival and melanin synthesis via multiple pathways in vitiligo
Niacinamide also demonstrated a protective effect against post-inflammatory hyperpigmentation: unlike in the benzoyl peroxide-only group, post-acne pigmentation did not increase significantly with the combination, suggesting a modulating effect on melanin production in inflammatory contexts
As with any supplement, check with a healthcare professional if you're pregnant, on medication, or managing a health condition
In skin care, they act as messengers, signalling skin to carry out specific tasks