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47 Even though there is heightened activity of glucouronidation and oxidative pathways, causing the increased clearance of APAP in pregnancy, no evidence exists to suggest pregnancy as a predisposing risk factor for APAP toxicity

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Additionally, MPP + has high affinity for noradrenergic and serotonergic uptake transporters [6,82], and its precursor, MPTP, has been mainly used in neuronal models with dopaminergic characteristics, such as the dopaminergic neuroblastoma cell line SH-SY5Y [83]

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