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guilliermondii , and Corynebacterium sp., lacking xanthine monophosphate (XMP) aminase, it was proven that the main precursor was guanine or a guanine nucleotide and the conversion of adenine, hypoxanthine, and xanthine to riboflavin passed through one of them ( 2 via serine, threonine, and glyoxalate cycles is a major rate-limiting factor for riboflavin overproduction

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