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The researchers grew mouse and human cells in the laboratory and treated them with AOD9604 to see how it changed the cells ability to burn fat

But its worth pointing out that there is no placebo group for this Reddit study, says Pinto

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While the FDA continues to monitor reports of suicidal thoughts, their 2024 safety communication found no clear evidence linking these medications to suicidal ideation

Contrary to common knowledge, patients in the subgroup with a higher BMI did not show significant weight gain (WMD = 1.21 kg, 95% CI 1.24 to 3.60, P = 0.33, I 2 = 72%) and there were no significant differences between the subgroups ( P = 0.73) (Additional file 2: Fig