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Table 5: Sensitivity Analysis
Based on elevated ghrelin concentrations found in individuals with PWS, in a 56-week study octreotide (long-acting somatostatin analog) significantly decreased fasting ghrelin concentrations (both acylated ghrelin, known to stimulate hunger, and unacylated ghrelin), but did not significantly affect weight, behavior, or appetite in nine adolescents with PWS
Research has also shown that GLP-1 inhibits beta cell apoptosis [1]
However, there was no statistical significance in GLP-1R expression between the OA and the OA + saline groups (Fig
Cancers 14:871
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