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This is important since imbalances in hormone biotransformation are implicated in the initiation of breast cancer through the generation of genotoxic metabolites (i.e., estrogen quinones) and reactive oxygen species (ROS), and the depletion of vital antioxidants and metabolic cofactors 10,11

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Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome [published correction appears in J Neurol Sci 2000 Jan 1;172(1):77]

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