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This was beyond the scope of the present study

Specific research areas include: Regulation of nitric oxide and endothelial signaling pathways Actin dynamics and cell migration processes Extracellular matrix deposition and remodeling Oxidative stress mitigation and redox balance Modulation of gene expression related to repair and immune signaling The combined formulation allows for the evaluation of overlapping and divergent signaling effects without the need for parallel administration protocols

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Different types of cells have different requirements for ATP, podocytes, endothelial cells and mesangial cells mainly use glucose for their energy supply, while renal tubular cells mainly use free fatty acids, glutamine, pyruvate, citrate and lactate as substrates for fuel supply through aerobic respiration (Scholz et al., 2021)

10.1007/s10549-020-05702-6 142 WuS.RheeK.-J.AlbesianoE.RabizadehS.WuX.YenH.-R.et al (2009)