The burden and treatment of diabetes in elderly individuals in the US
Research has identified specific gene variations that affect how individuals respond to these medications, influencing both appetite regulation and insulin sensitivity
The introduction of N-terminal ketone motifs into genetically encoded materials and their post-translational derivatization provides a paradigm for the programmed synthesis of peptide-derived materials that more closely resemble complex natural products
doi: 10.1111/dom.14048 Summary Keywords incretin, GLP-1, GIP, hyperinsulinism, dumping syndrome, bariatric surgery, fundoplication Citation Danowitz M and De Leon DD (2022) The Role of GLP-1 Signaling in Hypoglycemia due to Hyperinsulinism
SGLT2i receivers exhibited a 23 mmol/mol drop in HbA1c, and GLP1-RA recipients showed an 18 mmol/mol decrease in HbA1c of 6,856 individuals (8.0%), with an estimated HbA1c advantage on SGLT2 inhibitors of 5.0 mmol/mol