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doi:10.1097/JTO.0b013e3181d95dd4 33

Glutamate-cysteine ligase catalytic and modulator subunits as well as GSH synthetase are the three NRF2 targets involved in the GSH synthesis (242)

Most of these patients had a diagnosis of chronic fatigue syndrome

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The interplay between HAS3-mediated HA synthesis and HYAL1-driven degradation further exemplifies intrinsic temporal control of ECM remodeling, providing a natural biological model that parallels HAGSH scaffold responsiveness [19]