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Oxidative stress is when your body produces too many reactive oxygen species and doesnt have enough antioxidant capacity to neutralise them
Herein, the genetic susceptibility mechanisms of IBD, the specific impacts of environmental and lifestyle factors, and their interactive patterns are systematically reviewed, with particular emphasis on the mechanistic pathways of modifiable factors, with the aim of providing practical guidance for the development of personalized prevention strategies and therapeutic interventions
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270 Thus, the relationship among PS1 gene mutations or deficiencies, lysosomal acidification, and lysosomal calcium ion dysregulation warrants further investigation
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