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Diehl FF, Lewis CA, Fiske BP, Vander Heiden MG

Ghrelin is also involved in glucose homeostasis, as it inhibits insulin secretion and modulates insulin sensitivity, ultimately leading to increased blood glucose levels 80,81

Goal confusion: some patients stop once they've hit a weight loss target Access disruptions: drug shortages, prior auth delays, and pharmacy logistics all contribute

Peer review Peer review information Nature Chemical Biology thanks Jinwei Zhang and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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