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Dosing Schedules from Published Research Phase 2 Trial Dose Groups The Phase 2 clinical trial published in NEJM employed the following dose groups, all administered via subcutaneous injection once weekly: Scroll sideways to view the full table on mobile

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Dulaglutide offers another long-acting option, while Tirzepatide combines GIP and GLP-1 activity in a way that may enhance both weight management and glucose control

Medications Semaglutide, known by the brand name Wegovy, and liraglutide (Saxenda) have been specifically approved for weight loss in obesity, in combination with lifestyle changes

Step-up dosages: Participants then increased their dose strength every 4 weeks, first to 4 mg, then 6 mg, then 9 mg, then 12 mg, depending on their assigned maintenance dose