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The progression of CLDs is frequently accompanied by severe complications such as infections, gastrointestinal bleeding, and hepatic encephalopathy, which contribute to their high mortality

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) and has been transmitted to the Congress and the Comptroller General for review

In the case of ferroptosis-driven acute liver injury, Gpx4 HEPKO mice showed highly elevated ALT, AST, and LDH levels concomitant with severe cell death and morphological liver tissue changes (Fig

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