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Individuals who encounter retatrutide outside of a regulated clinical trial for example, through unregulated online suppliers should be aware that such products are unlikely to meet the quality standards required of licensed medicines in the UK

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TRIUMPH-3 (NCT05882045) is a Phase 3, 80-week, randomized, double-blind, placebo-controlled trial investigating the efficacy and safety of retatrutide once weekly compared with placebo in participants with severe obesity (Class 2 or Class 3), defined as BMI 35 kg/m 2 , and established cardiovascular disease