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Additionally, a study on depressed adolescent patients reported volume decreases in several brain regionsincluding the cingulate cortexwith greater reductions associated with longer durations since MDD onset 74 .The Hip was also investigated in depressed adolescent patients, and abnormalities were found in the CA regions and DG, subfields primarily associated with memory impairments 75

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Individual Metabolism and Tolerance Everyone metabolizes medications differently

This can compromise detox capacity, impair recovery, and accelerate aging