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Injectable hydrogels Injectable hydrogels are stimuli-responsive polymeric networks designed to undergo sol-to-gel transitions under physiological conditions, thereby enabling localized and sustained drug delivery via minimally invasive SC administration [44]

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Doherty et al

Provider assessment of pre-existing gastrointestinal tolerance is therefore essential before initiation

Note: animal studies indicate that high doses of DPP-4 inhibitors & GLP-1 agonists cause expansion of cells of the pancreatic ductal glands and can cause premalignant pancreatic intraepithelial lesions (PanIN) that have the potential to progress to pancreatic adenocarcinoma