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Since gp34 is known to antagonize antibody-mediated host FcR activation (Corrales-Aguilar et al, 2014), we first hypothesized that gp34 1-179 might modulate B cell function by interacting with IgGs bound to CD32b (Dickler and Kunkel, 1972)

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doi: 10.1038/s41590-021-00996-0 64 WangWGreenMChoiJEGijnMKennedyPDJohnsonJKet al

MOMP results in the release of mitochondrial intermembrane space proteins, most notably cytochrome c, into the cytosol

It also balanced apoptosis by lowering harmful proteins (Bax, Caspase-3) and increasing protective ones (Bcl-2)