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Furthermore, cytokines released by astrocytes may bind to their specific receptors in the dopaminergic neurons, such as TNFR1 and 2, and activate proapoptotic mechanisms through the activation of caspase 3, caspase 8, and cytochrome c [10]

Current wound management approaches focus on scavenging ROS 23,24 , mitigating inflammation 25,26 , modulating immunity 27,28 , and enhancing tissue regeneration 29,30

ClC3 is a critical regulator of the cell cycle in normal and malignant glial cells