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Neurotransmitters and neuromodulators: handbook of receptors and biological effects

Tendon collagen turns over slowly, the blood supply to tendons is inherently limited, and the mechanical demands on tendons mean they need to rebuild strength progressively rather than all at once

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Notably, the age-related increases in nitration of ECM-bound HGF were predominant on fast IIa and IIx myofibers 32 , corresponding with the fast fiber-preference observed in age-related muscle atrophy and impaired regeneration in humans in which fast IIb fibers are scarce 33,34,35, 39