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This is similar to the considerations around how long reconstituted peptides last in the fridge after preparation

A phase 1 study using CD19+BCMA CAR-T mapped autoreactive clones to marrow plasma cells and showed these cells persist after single-target therapy but are eliminated with dual targeting (Feng J et al

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More recently, irritability has also been recognised as a core antecedent of depression in young people 7 , therefore playing an important etiological role in the development of depressive states

(301) demonstrated that combination treatment with SGLT2 inhibitors and other cardio-renal protective agents significantly extends cardiovascular event-free, kidney event-free, and mortality-free survival in patients with type 2 diabetes and albuminuria