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Xenobiotics conjugate with glutathione, and hence a higher concentration of the enzyme is required for conjugation to make the toxin neutral and thereby making the enzyme less available as an antioxidant

Tuvesson H, Gunnarsson PO, Seidegard J

From a cardiovascular perspective, Vitamin B12 nasal spray helps lower homocysteine levels in the blood, a compound associated with an increased risk of heart disease

Thomas JM, Ling YH, Huuskes B, Jelinic M, Sharma P, Saini N, Ferens DM, Diep H, Krishnan SM, Kemp-Harper BK, et al