Cancer 73 : 707714 Marchetti P, Castedo M, Susin SA, Zamzami N, Hirsch T, Macho A, Haeffner A, Hirsch F, Geuskens M and Kroemer G (1996) Mitochondrial permeability transition is a central coordinating event of apoptosis
Glutathione: in defence of the lung
The peptide's ability to increase superoxide dismutase activity is particularly significant, as SOD catalyzes the dismutation of superoxide radicals into less harmful molecules, providing a first line of defense against oxidative stress
This pentadecapeptide (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) demonstrates remarkable physicochemical stability across diverse biological environments, including resistance to gastric acid degradation and enzymatic hydrolysis, which facilitates multiple routes of administration including enteral delivery
Copper, as a transition metal, plays a critical role in enzymatic systems related to redox balance, mitochondrial function, and connective tissue integrity
