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In the ATTAIN-MAINTAIN trial, participants transitioning from Wegovy to oral Foundayo (orforglipron) began SURMOUNT-5 at an average body weight of 113.5 kg (250.2 lbs)

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Additionally, FOXO4-DRI influences antioxidant enzymes such as manganese superoxide dismutase and glutathione peroxidase, further mitigating oxidative stress and promoting cellular health

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Etiologically, MetS are associated with a sedentary lifestyle (Edwardson et al., 2012), cellular inflammation, and OS mechanisms (Bonomini et al., 2015) that may be involved in the onset of vitiligo

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