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(C) GRs of Zabius fuscus, note granules in the cytoplasm and short cytoplasmic extensions

The observed upregulation of oxidative and lipolytic gene networks, together with metabolomic signatures indicating enhanced -oxidation, reduced accumulation of acyl-carnitines, and restoration of peroxisome activity, support the notion that Retatrutide is associated with pronounced adipose metabolic reprogramming toward a catabolic state

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