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doi: 10.1016/j.numecd.2024.09.028
GLP-1 is an incretin hormone that enhances insulin secretion in response to meals and promotes satiety
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This strategic design allows researchers to fully engage the GIP pathway for enhanced metabolic effects while minimizing the dose-limiting gastrointestinal tolerability issues common with high-dose GLP-1 agonism, making it uniquely valuable for studying synergistic incretin mechanisms
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