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Micronized progesterone, which more closely mirrors the molecular structure of the body's own progesterone, has largely replaced the older synthetic progestins used in the original WHI trial, and appears to offer improved tolerability and a more favorable safety profile [11,27]

FDA has issued specific warnings about unapproved GLP-1 products sold online, including semaglutide and tirzepatide labeled for research use only or compounded preparations with dosing errors and safety concerns

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