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Women in their 40s, 50s, and 60s are now among the fastest-growing groups using GLP-1s for weight loss

But, notably, 24 h treatment of NSBSO showed strong cytotoxicity against MCF-7, B16, A549 and 4T1 cells, with IC 50 values of 1.074, 0.844, 1.222 and 4.741 M, respectively, which were much lower than those of reported GSH-responsive peptide derivatives whose IC 50 was greater than 100 M [43]

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Studies were also excluded if they focused on participants with primary testicular disease, including Klinefelter syndrome, testicular tumors, or severe varicocele, or if they involved men with pituitary or hypothalamic organic diseases, such as prolactinomas or hypopituitarism