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Quick Comparison Table How Topical GHK-Cu Works Topical GHK-Cu operates through a well-characterized mechanism: the tripeptide-copper complex penetrates the outer skin layers and accumulates as a depot in the epidermis and upper dermis, where it exerts localized effects on fibroblasts, keratinocytes, and extracellular matrix components

Chen W, Wang Y, Pan Z, Chen X, Luo D, Wang H

2022 Nov;21(11):100460 Matei VP, Rosca AE, Pavel AN, Paun RM, Gmel G, Daeppen JB, et al