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This sensitization to TGF-beta signaling augments expression of matrix genes including collagens, fibronectin, and proteoglycans, while appropriate regulation prevents excessive TGF-beta activity associated with pathological fibrosis

These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione

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The peptide appears to enhance mucosal blood flow and promote angiogenesis within the gastric mucosa, which contributes to its protective and healing properties

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