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So, it may take several years for the anemia to develop after absorption of the vitamin has stopped

in hypophysectomized rats treated with T3 and/or human GH by the continuous infusion of hormone for 6 days

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[2] The result is vasoconstriction and increased systemic vascular resistance, which can be therapeutically useful in conditions like vasoplegic shock where pathological vasodilation has caused life-threatening hypotension