To date, numerous drugs containing antioxidant-like substances have been investigated to either support or replace standard treatments for vitiligo (Table 1)
Key Points Tendon disorders are common, often under-reported and a major clinical problem Most current treatments for tendinopathy are neither effective nor evidence-based Molecular processes underlying tendinopathy are now being elucidated: metalloproteinase enzymes are thought to have a key role in the regulation of the activity of tendon cells and matrix remodeling in both normal and pathologic tendon The potential roles of neuropeptides, inflammatory mediators and mechanical strain (either too much or too little) acting on the resident tenocytes are the source of some controversy and require in-depth investigation using in vitro and in vivo models Excessive or inappropriate activity of destructive matrix-degrading enzymes might be a novel therapeutic target for tendinopathy
This is exactly the kind of substitution that inflates the apparent evidence base: a study on one copper peptide gets quietly relabeled as proof for another
Topic selection A total of 1290 hospitalised patients in our hospital who were prescribed injectable PPIs (including omeprazole, pantoprazole, esomeprazole, lansoprazole and ilaprazole) were selected for this research, which was conducted from November to December 2023
Water, Ethylhexyl Methoxycinnamate, Butylene Glycol, Ethylhexyl Salicylate, Octocrylene, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Butyl Methoxydibenzoylmethane, Dipropylene Glycol, Niacinamide, Squalane, C14-22 Alcohols, 1,2-Hexanediol, Polyglyceryl-2 Stearate, Propanediol, Hydroxyacetophenone, Glyceryl Stearate, Stearyl Alcohol, C12-20 Alkyl Glucoside, Tromethamine, Centella Asiatica Extract, Carbomer, Melaleuca Alternifolia Extract, Hippophae Rhamnoides Fruit Extract, Vitis Vinifera Fruit Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Uncaria Sinensis Extract, Glycerin, Adenosine, Disodium EDTA, Oryza Sativa Bran Extract, Hydrogenated Phosphatidylcholine, Caprylic/Capric Triglyceride, Sodium Hyaluronate, Glucose, Hydrolyzed Collagen, Sucrose Stearate, Glutathione, Cyclodextrin, Cetearyl Alcohol, Caprylyl Glycol, Beta-Glucan, Caprylhydroxamic Acid, Ethylhexylglycerin, Asiatic Acid, Asiaticoside, Madecassic Acid, Madecassoside, Tropolone, Hyaluronic Acid, Potassium Hyaluronate *Due to changes in production, the manufacturer may, in rare cases, make short-term changes to the ingredients used
