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Ferroptosis is involved in regulating the occurrence and progression of diseases such as cancer, respiratory system diseases, cardiovascular system diseases, diabetes mellitus, and urinary system diseases and plays a key role in disease treatment (11) ( Figure 1 )

Within the antioxidant defense system, the fat-soluble vitamin E directly neutralizes lipid radicals within membrane phospholipids, effectively halting the chain reaction of lipid peroxidation

The limitations of this study include a short study period, lack of follow-up, lack of measurement of serum glutathione levels and the choice of cohort, which consisted of a young and healthy population

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