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In its response [15], the ACOG concluded that available studies show no clear evidence that proves a direct relationship between the prudent use of APAP during any trimester and fetal developmental issues. The ACOG further concluded that physicians should not change clinical practice until definitive prospective research is done. Considering the ACOG response, it is important to note that evidence of APAP inducing neurodevelopmental problems during the prenatal period is concerning but limited [2,16,17]

According to the Centers for Disease Control and Prevention (CDC), NSAIDs are widely recommended for conditions like arthritis, muscle pain, and post-surgical recovery due to their strong anti-inflammatory properties

Before : Uneven skin tone, hyperpigmentation, sun spots, or dull skin

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1994 Oct;2(4):259-69