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Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

The samples were then sonicated in ice-cold water using Biorupter UCD-200 sonicator for 5 min (30 s sonication and 30 s rest cycle

We continue to believe that if market-based data (median payer-specific negotiated charges for MA organizations) are incorporated into the calculation of the MS-DRG relative weights, initially there will be limited impact on the relative weights given the current similarity between MA organization rates and Medicare FFS rates, but that over time the proposal would create an opportunity for negotiations to reflect market dynamics, as noted by a commenter who supported our proposed policy

This is particularly important for medications with a narrow therapeutic index or those requiring rapid onset of action