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Currently, there are no evidence-based guidelines, particularly regarding endoscopic procedures, on whether to hold these medications or how to adjust fasting protocols for this patient population

Observational and interventional studies have consistently shown stronger anti-addictive effects of GLP-1RAs in individuals with obesity or insulin resistance

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Although insulin resistance is present independently of BMI, this study highlights that insulin resistance worsens by increased BMI irrespective of visceral fat accumulation, supporting inherent insulin resistance

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